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Investigator Initiated Trial of the LSD1 Inhibitor IMG 7289 for the Treatment of Patients With Essential Thrombocythemia ET or Polycythemia Vera PV That Have Failed at Least One Standard Therapy Actual Study Start Date October 2 2020 Estimated Primary Completion Date October 31 2024 Estimated Study Completion Date

A Phase 2 Study of the LSD1 Inhibitor Bomedemstat IMG 7289 for the Treatment of Advanced Myelofibrosis MF Updated Results and Genomic Analyses Blood American Society of Hematology 634 Myeloproliferative Syndromes Clinical and Epidemiological November 15 2022

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Bomedemstat IMG 7289 an LSD1 Inhibitor Manages the Signs and Symptoms of Essential Thrombocythemia ET While Reducing the Burden of Cells Homozygous for Driver Mutations ScienceDirect View PDF Search ScienceDirect Blood Volume 142 Supplement 1 2 November 2023 Page 747 Oral Abstracts

A Phase 2 Study of the LSD1 Inhibitor Img 7289 bomedemstat for the Treatment of Advanced Myelofibrosis ScienceDirect View PDF Search ScienceDirect Blood Volume 138 Supplement 1 23 November 2021 Page 139 634 Myeloproliferative Syndromes Clinical and Epidemiological

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Bomedemstat Ditosylate IMG 7289 Ditosylate LSD1 Inhibitor

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Bomedemstat Ditosylate IMG 7289 Ditosylate LSD1 Inhibitor


Official Title A Multi Center Open Label Extension Study Evaluating the Safety and Efficacy of Bomedemstat for the Treatment of Patients With Myeloproliferative Neoplasms MPNs Enrolled in a Prior Bomedemstat Clinical Study Actual Study Start Date December 16 2021

Brief Summary This is an open label Phase 2 study of bomedemstat IMG 7289 an inhibitor of lysine specific demethylase 1 LSD1 in combination with JAK inhibition JAKi in patients with myelofibrosis Study Design Go to Resource links provided by the National Library of Medicine MedlinePlus Genetics related topics Primary

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A Phase 2 Study Of The LSD1 Inhibitor Bomedemstat IMG 7289

https://ashpublications.org/blood/article/140...
A Phase 2 Study of the LSD1 Inhibitor Bomedemstat IMG 7289 for the Treatment of Advanced Myelofibrosis MF Updated Results and Genomic Analyses Blood American Society of Hematology 634 Myeloproliferative Syndromes Clinical and Epidemiological November 15 2022

 IMG 7289
A Phase 2 Study Of The LSD1 Inhibitor Img 7289 bomedemstat

https://ashpublications.org/blood/article/138...
IMG 7289 CTP 201 is a global open label Phase 2b study of bomedemstat taken once daily for 24 weeks in patients with ET who are resistant to or intolerant of at least one SOC treatment NCT04254978

A Phase 2 Study of the LSD1 Inhibitor Bomedemstat IMG 7289 for the Treatment of Advanced Myelofibrosis MF Updated Results and Genomic Analyses Blood American Society of Hematology 634 Myeloproliferative Syndromes Clinical and Epidemiological November 15 2022

IMG 7289 CTP 201 is a global open label Phase 2b study of bomedemstat taken once daily for 24 weeks in patients with ET who are resistant to or intolerant of at least one SOC treatment NCT04254978

img-7289-angie-six-flickr

IMG 7289 Angie Six Flickr

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IMG 7289 LewisTalkWA

img-7289-burlington-business-association

IMG 7289 Burlington Business Association

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IMG 7289 Dreesch7

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IMG 7289 YouTube

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IMG 7289 Blog Di Viaggi